CR Prairie is the team to beat in 4A, in my opinion, with Johnston right there with them.
CR Jeff will be very solid. IC West will still be good but down a bit from the last couple of years. The Mississippi side of MVC will be much stronger than the Valley.
In the CIML, Waukee will also be strong, and Valley & SE Polk will be not far behind. I know Dowling has gotten some run (I think Feddersen has them ranked #1), but I don't think they will end up in that position. I could certainly be wrong though. Western Dubuque will be good too, but I'm not sure they have the hitting to compete with the big dogs. The same goes for Indianola.
In 3A, Davenport Assumption will likely come out on top, but Carlisle might be my early favorite. Harlan and Solon will be there in the end as well. I'm not as familiar with the 3A schools on the eastern side of the state. Osky will still be good, but they have to replace a pretty strong graduating class from a batting perspective anyway.
In 2A, Beckman will be the favorite, but Wilton, Cascade, Treynor, & IC Regina will be good and could contend.
1A will be interesting as well, though you could probably flip a coin between North Linn & Newman. There is lots of depth there, though, with CB St. Albert, Lisbon, Remsen, & Don Bosco all having strong teams. Beyond that, the quality drops off a bit, in my opinion.